Players assume the role of Prophet as he returns to New York, only to realize that the city has been encased in a Nanodome constructed by the corrupt Cell Corporation. The New York City Liberty Dome is a veritable urban rainforest teeming with overgrown trees, dense swamplands and teeming rivers. Within the Liberty Dome, 7 distinct and treacherous environments become known as the Seven Wonders. This dangerous new world requires the use of advanced weapons and tactics. Prophet will don a lethal composite bow, an enhanced Nanosuit and devastating alien tech to become the deadliest hunter on the planet.